Before initial dose, depress pump spray 4-5 times to prime. Hold King Bio’s medically metered pump spray right up to your lips very close to mouth and spray one dose under your tongue. The adult dose is two complete pump sprays. Doses should be taken orally and held under the tongue for 30 seconds, then swallowed. Holding the formula under the tongue provides faster absorption as well as faster results. For best results, take doses between meals or at least 10 minutes or more away from meals. Allow a minimum of 10 minutes between doses if taking more than one King Bio Natural Medicine.